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Amelioration of Experimental Autoimmune Encephalomyelitis and Expression of IL-10、TGF-β1 in Rats b
Objective:Sinomenine,a alkaloid monomer extracting from a plant Sinomenium acutum,has been used to relieve rheumatoid arthritis in human having well therapeutic effect and a few side effect.Recent studies have shown that sinomenine possesses....
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The Effect of Renal Tubular Epithelial-myofibroblast Transdifferentiation in High Glucose and the Inf
Background and objectives:Diabetic nephropathy(DN)is one of blood capillary complications. Tubulointerstitial fibrosis is an essential pathological basis in the progression of diabetic nephropathy to end stage renal disease(ESRD), the basic....
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Effect of Renal Tubular Epithelial-myofibroblast-transdifferentiation and MMP-9/TIMP-1 on DN and the
Background and objectives:Diabetic nephropathy is one of the main causes of chronic renal failure.Tubulointerstitial lesion is an essential pathological basis in the development of chronic kidney disease including diabetic nephropathy to end....
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The Proapoptotic Effect of AngiotensinⅡ on Renal Tubular Epithelia Cells and the Protective Effect
Objective To investigate the mechanism that AngⅡinduce the apoptosis of cultured NRK-52E and the protective effect of Cordyceps Sinensis(CS).Methods Cutlture cells,rat renal tubular epithelia cells (NRK-52E),were randomly divided into five....
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The Fermentation of Codonopsis Pilosula with Pleurotus Ostreatus and Application of Fermentation Brot
Fungi Pleurotus ostreatus(P.ostreatus)have many fine characteristics,like strongly reproductive Capacity,simple nutriments requirements,easy culture et al.Moreover,the P. ostreatus can produce abundant enzymes that can decompose traditional....
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Bioleaching of Realgar, Bacteriostasis Function and Medical Efficacy of Realgar Microorganism Lixiviu
Realgar,a naturally occurring arsenical sulfide has been combined with Chinese herbal medicine as a mineral Chinese traditional medicine.Realgar and some compounds with realgar have many curative effects.It is very important in Chinese tradi....
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Allicin-Induced Apoptosis in EL4 Murine T-lymphocytes in Vitro
Garlic(Allium sativum L;Liliaceae)has played an important dietary and medicinal role throughout the history of mankind.Allicin is one of the most biologically active organics sulfur compounds(OSC)in garlic extracts,which owns powerful therap....
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Effects of Calming the Liver and Suppressing the Hyperactive Yang Recipe on Hypothalamuses and Adrena
Objective:To analyse the different expression proteins of rat hypothalamuses and adrenal glands from normal group、hyperthyroidism group with hyperactivity of liver-yang(model group)and the treated group by pinggan-qianyang Chinese medicine....
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The Effect of Tetramethylpyrazine on the Expression of IL-10、IL-18 after Acute Spinal Cord Injury i
OBJECTIVE: To study the effect of Teramethylpyrazine (TMP) on expression of IL-10 and IL-18 in acute spinal cord injury(ASCI) in rats and approach the protective effect and possible mechanism of TMP in ASCI.METHODS : 88 SD rats weighting 250....
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The Effects of Yi-Qi Huo-Xue Chinese Herbs on Expressions of TSP-1、TSP-2 and Their Receptor CD36 Pr
Object and Background:intracerebral hemorrhage(ICH) accounted for 35%of cerebral vascular disease,had a high morbidity and mortality,the mortality Within 30 days was 50%,40%of the survivors left with severe disabilities,Only 10%of patients a....
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The Effects of Yi-Qi Huo-Xue Chinese Herbs on Expressions of Angiopoietin-1 and Its Receptors Tie-2 i
Background and Object:Intracerebral Hemorrhage (ICH), with its high incidence, death and disability rate, is seriously threatening to people's healthy. Its incidence account for 30% of all kind of cerebrovascular disease (CVD), It's death ra....
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Effect of Xuebijing Injection on Regulatory Dendritic Cells in Mouse
Subject:Effect of Xuebijing Injection on Regulatory Dendritic Cells in MousePolymicrobial sepsis is associated with immunosuppression caused by the predominance of anti-inflammatory mediators and profound loss of lymphocytes through apoptosi....
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A Study on Antimicrobial Activity of Garlicin on Enterococcus Faecalis in Vitro
Objective: To campare the bacteriostatic and bactericidal action of garlicin, calcium hydroxide and sodium hypochlorite on Enterococcus faecalis in vitro, and to provide the envidence for the clinical use of the garlicin.Methods: 1. Sensitiv....
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Studies on Polygona-polysaccharose's Effects upon APP Transgenic Mice's Learning Ability & Memory and
Alzheimer's disease (AD) is the degeneration of the central nervous system (CNS). It's clinically characterized by impairment of memory Transmission Electron Microscope (TEM) was used to observe the ultrastructure of hippocampus; Stereology....
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The Toxiological Study on Alcohol Extract of Centipedes
Objective: To find the safe and effective dose of clinical treatment and provide a theoretical basis by the toxiological study on Alcohol Extract Of CentipedeMethod: To study the effects of the animals' toxic response , changes of histopatho....
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The Mechanism of Treating HSK Mice Model with Yupingfeng Powder
Purpose: To investigate the mechanism of Yupingfeng Powder in curing mice with infection of herpes simple virus type 1 (HSV-1).Methods: Sixty Balb/c mice were divided into three groups randomly: normal control group, treatment group and mode....
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The Polygona-Polysacch-Arose's Effects upon APP Transgenic Mices' Expression of NOS in the Brian and
With the close relation of aging and the prolonging of the age , the morbidity of Alzheimer's disease is greatly increasing .It is the forth cause of death in old people's disease.The onset and progress of patient's condition is influenced b....
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Experimental Study of Breast Carcinoma Treatment by Extract of Centipedes
Objective:To investigate the effects and mechanisms of breast carcinoma MCF-7 treatment with ECP,and provide rational for breast carcinoma MCF-7 clinical treatment with EVP.Methods:1.To set up model of MCF-7 breast carcinoma in nude mouse,an....
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Exploration of the Molecular Mechanism of HL-60 Cell Apoptosis Induced by Lycorine
Leukemia is one of the most threatening hematological malignant cancer today and chemotherapy remains the conventional method in treatment.Lycorine is one of alkaloids extracted from Amaryllidaceae family,showing a strong natural anti-cancer....
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Effects of Chronic Psychological Stress on Glucose Metabolism and the Ameliorative Effects of Rehmann
ObjectiveThis thesis focuses on the establishment and evaluation of the best method for inducing rat model of insulin resistance by chronic psychological stress,and the investigation of the ameliorative effects of Rehmannia glutinosa oligosa....